Table 1.

Cell death regulatory genes activated or suppressed after irradiation

Mechanism/Pathway	Transcription	Post- transcription	Protein modification	Translocation
Mitochondria	Bcl-2, Bcl-XL, Bcl-W, Bax, Bak, Bid, Noxa, hac-1, etc.		Bid, Bcl-2,
Iap/antagonist	Ciap1, reaper, hid, sickle, etc.	Xiap		Smac, HtrA2
Death receptor	Fas, FasL, Trail, DR5, DcR2, DcR3, Tradd, etc.

List of core cell death regulatory genes/proteins that have been reported as being activated or suppressed in response to irradiation. Drosophila genes are italicized.