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Nonsteroidal anti-inflammatory drug (NSAID) adverse effects
| Adverse effects of most concern | |
|---|---|
| Gastrointestinal | Gastrointestinal ulceration and intolerance |
| Renal | Inhibition of prostaglandin-mediated renal function |
| Hemostatic | Blockade of platelet function |
| Pregnancy | Inhibition of uterine motility may prolong gestation |
| Immune | Hypersensitivity reactions |
| Cardiovascular | Increased blood pressure |
| Interactions | Warfarin: NSAIDs bind to plasma proteins and can displace from binding site |
