TABLE 5.

Risk factors for the development of nonsteroidal anti-inflammatory drug (NSAID)-associated gastroduodenal ulcers

Established risk factors	Advanced age (>70 years) History of ulcer Concomitant use of steroids Higher doses, use of more than one NSAID Concomitant use of anticoagulants Serious systemic disorder
Probable risk factors	Infection with Helicobacter pylori Cigarette smoking Consumption of alcohol