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. 2008 Nov 19;105(48):18735–18739. doi: 10.1073/pnas.0810518105

Fig. 3.

Fig. 3.

Consequences on cell growth due to the mtETC recovery by AOX or NDI1 and AOX expression. (Inset) Frequency distribution of the growth and/or death rates (as negative values) obtained for each cell type and adjusted to a normal distribution. ρ+ cells, black profile; ρ° cells, red profile; ρ°AOX cells, blue profile; ρ°NDI1/AOX, green profile. Effect of AOX or NDI1+AOX expression on cell growth (DT) and survival under the indicated culture conditions. Data for different media are expressed as mean ± standard deviation being n (from left to right in the figure) = 3, 3, 4, 4, 5, 5, 3, 3, 3, 3, 4, 5 for ρ+; n = 3, 3, 4, 4, 4, 4, 3, 3,3, 3, 4, 5 for ρ°; n = 3, 3, 4, 3, 5, 3, 3, 3, 3, 3, 4, 4 for ρ°AOX; n = 3, 3, 4, 3, 4, 3, 3, 3, 3, 3,4, 4 for ρ°NDI1/AOX. The significance of the mean differences was determined by the ANOVA, Fisher's PLSD test. Gal, galactose; Glu, glucose; DCA, sodium dichloro acetate (15 mM); Uri, uridine (0.2 mM); Pyr, pyruvate (1 mM); CM, complete medium containing uridine and pyruvate; dFBS, dialyzed fetal bovine serum.