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Location of inactivating amino acid substitutions in M photopigments in dichromats. Circles represent amino acids with the amino terminus in the lower left and carboxyl terminus in the upper right. The seven transmembrane alpha helical segments are labeled (helix 1-6). Amino acid positions 203 and 187 are indicated. The disulfide bond that is normally formed by cysteine residues at positions 126 and 203 is indicated by a dashed line.
