Table 3.

Multigene protanopes

					M gene sequencesc
Subject ID	% L genes	% Downstream genes	No. L genes	No. M genes	Exon 2 65111116	Exon 3 153171174176180	Exon 4 204230233 236	Mutation	Predicted Δλmax (nm)
JB122273b	31.01	73.61	1	4	I V Y	M V A I A	C T S V	L gene last	0
RS072630b	43.3	53.79	1	1	not done	not done	not done	TISLIAVAIAMd	0
DT090543b	1.87	65.79	0	3	T/I I/V S/Y	L V A I A	C/R T S V	C203R	0
54a	1.57	47.22	0	2	T/I I/V S/Y	L V A I A	C/R T S V	C203R	0
48a	0.56	62.65	0	3	I V Y	L/M V A I A	C/R T S V	C203R	0
GP041934b	0	51.92	0	2	I V Y	M V A I A	C T S V	none found	0
BS070784b	0	55.3	0	2	I V Y	M V A I A	C T S V	none found	0
167a	7.73	55.81	0	2	I V Y	M V A I A	C T S V	none found	0
BW112726b	1.06	56.57	0	2	I V Y	M V A I A	CT S V	none found	0
SS091021b	0	82.78	0	5	I V Y	M V A I A	C T S V	none found	0
VJ022026b	0	70.37	0	3	I V Y	M V A I A	C T S V	none found	0
27a	0	71.87	0	3	I V Y	M V A I A	C T S V	none found	0
JH082574b	0.83	62.82	0	3	I V Y	M V A I A	C T S V	none found	0
166a	8.09	57.84	0	2	I V Y	M V A I A	C T S V	none found	0
20a	0	48.59	0	2	I V Y	M V A I S	C T S V	none found	0
DM081241b	0.17	71.62	0	3	I V Y	M V A V A	C T S V	G -425 Ae	0
141a	0	51.15	0	2	I V Y	M V V V A	C T S V	none found	0
AT052178b	0	48.16	0	2	I V Y	M V A/V I/V A	C T S V	none found	0
174a	6.4	55.36	0	2	I V Y	M V A/V I/V A	C T S V	G -425 Ae	0
CW121741b	0.62	48.74	0	2	T I/V S/Y	L/M V A I A	C T S V	none found	0
RW061526b	0.14	50.72	0	2	T/I I/V S/Y	L V A I/V A	C T S V	none found	0
10a	3.05	47.17	0	2	T/I I/V S/Y	L/M V A I A	C T S V	none found	0
105a	4.22	50.73	0	2	T/I I/V S/Y	L/M V A I A	C T S V	none found	0
RL052633b	2.14	54.51	0	2	T/I I/V S/Y	L/M V A I A	C T S V	none found	0
178a	3.25	57.15	0	2	T/I I/V S/Y	L/M V A I S	C T S V	none found	0
139a	4.58	48.22	0	2	T/I I/V S/Y	L/M V A/V I/V A	C T S V	none found	0
TT010182b	0	48.13	0	2	T/I I/V S/Y	M V A I A	C T S V	none found	0
JH101146b	1.28	47.84	0	2	T/I I S/Y	M V V V A	C T S V	G -425 Ae	0
BM072774b	1.3	54.98	0	2	T/I I/V S/Y	M V A I S	C T S V	A -71 Ce	0
CB050289b	1.03	67.23	0	3	T/I I/V S/Y	L/M V A I A	C T S V	none found	0
JW092022b	0.57	67.28	0	3	T/I I/V S/Y	L/M V A I A	C T S V	none found	0
JB111483b	0.16	64	0	3	T/I I/V S/Y	M V A I A	C T S V	none found	0
HH122516b	0	64.67	0	3	T/I I/V S/Y	M V A I A	C T S V	none found	0
49a	0.39	66.38	0	3	T/I I/V S/Y	M V A I A	C T S V	none found	0
33a	0.36	63.54	0	3	T/I I/V S/Y	M V A I/V A	C T S V	none found	0
126a	2.92	66.67	0	3	T/I I/V S/Y	M V V V A	C T S V	none found	0
135a	0.28	42.29	0	2	T/I I/V S/Y	L/M V A I A	C T/I S/A V/M	none found	1.5

^aRayleigh matches were obtained with a Nagel Type I anomaloscope.

^bRayleigh matches were obtained with a Neitz OT1 anomaloscope.

^cSingle letter amino acid code: A = alanine, C = cysteine, I = isoleucine, L= leucine, M = methionine, R = arginine, S = serine, T = threonine, V = valine, Y = tyrosine.

^dSingle letter amino acid code indicating amino acid found at positions 65, 111, 116, 153, 171, 174, 178, 180, 230, 233, and 236 of L pigment gene.

^eMutation in promoter region of downstream gene, numbering convention counts backward from mRNA start site which is +1.