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Effect of known blockers on Ca2+ activated Cl- channel. (A) Trace of Ca2+ activated Cl- channel current before and during application of flufenamic acid (FA). (B) Dose response relation of flufenamic acid block of Ca2+ activated Cl- current. (C) Summary of IC50s of commercially available blockers for Ca2+-activated Cl- channel. n indicates number of oocytes. Error bars indicate SEMs.
