Table 1.
IC50s of known blockers and anthranilic acid derivatives.
| Compound number | Chemical compound | IC50 * | IC50 | n |
| a-1 | DIDS | 48 | 10.7 | 6 |
| a-2 | NPPB (5-nitro-2-(3-phenylpropylamino)benzoic acid) | 22–68 | 32.3 | 6 |
| a-3 | 9-AC (9-anthracene carboxylic acid) | 10.3 | 94.3 | 5 |
| a-4 | Niflumic acid | 17 | 37.3 | 7 |
| a-5 | Flufenamic acid (N-(3-Trifluoromethylphenyl)anthranilic acid) | 28 | 35.4 | 6 |
| a-6 | Mefenamic acid | 44.5 | 6 | |
| a-7 | N-Phenylanthranilic acid | 88.1 | 6 | |
| a-8 | 5-Nitro-N-phenylanthranilic acid | 42.5 | 8 | |
| b-1 | N-(2-Nitrophenyl)anthranilic acid | LP | 7 | |
| b-2 | N-(3-Nitrophenyl)anthranilic acid | 32.1 | 7 | |
| b-3 | N-(4-Nitrophenyl)anthranilic acid | 17.8 | 6 | |
| b-4 | 5-Nitro-N-(4-nitrophenyl)anthranilic acid | 15.4 | 5 | |
| b-5 | N-(2-Trifluoromethylphenyl)anthranilic acid | 29.5 | 6 | |
| b-6 | N-(4-Trifluoromethylphenyl)anthranilic acid | 6.0 | 6 | |
| b-7 | N-(4-Fluoro-3-trifluoromethylphenyl)anthranilic acid | 14.7 | 6 | |
| c-1 | N-(4-Fluorophenyl)anthranilic acid | 63.1 | 6 | |
| c-2 | N-(4-Chlorophenyl)anthranilic acid | 11.3 | 6 | |
| c-3 | N-(4-Methylphenyl)anthranilic acid | 55.3 | 7 | |
| c-4 | N-(4-Isopropylphenyl)anthranilic acid | 17.0 | 6 | |
| c-5 | N-(4-tert-Butylphenyl)anthranilic acid | 22.9 | 7 | |
| c-6 | N-(4-Decylphenyl)anthranilic acid | LP | 6 | |
| c-7 | N-(4-Methoxyphenyl)anthranilic acid | 102.3 | 5 |
IC50 * means IC50 previously studied. LP: Low Potency. IC50 > 200 μM n indicates number of oocytes.