Table 4.
Cartilage matrix proteins and modifying enzymes upregulated in adult cartilage relative to neonatal cartilage
| Gene Name | Gene Symbol | GenBank ID(s)† | Fold Change (A/N) | p-value |
| Cartilage intermediate layer protein | CILP | CX598636.1 | 5.96 | 0.0102 |
| CX599486.1 | 7.83 | 0.0042 | ||
| Cartilage oligomeric matrix protein | COMP | CX592689.1 | 2.53 | 0.0036 |
| CX592951.1 | 2.25 | 0.0014 | ||
| CX593277.1 | 2.09 | 0.0164 | ||
| CX597915.1 | 2.63 | 0.0041 | ||
| CX600749.1 | 2.43 | 0.0035 | ||
| CX601142.1 | 2.29 | 0.0038 | ||
| Fibronectin | FN1 | CX594011.1 | 4.65 | 0.0075 |
| CX596432.1 | 3.35 | 0.0192 | ||
| CX598808.1 | 3.86 | 0.0313 | ||
| CX600436.1 | 4.18 | 0.0024 | ||
| CX601190.1 | 4.62 | 0.0017 | ||
| CX602630.1 | 1.31 | 0.1717 | ||
| peFN840 | 6.03 | 0.0013 | ||
| peFN-C1 | 7.24 | 0.0018 | ||
| Frizzled-related protein | FRZB | CX597477.1 | 3.53 | 0.0159 |
| CX598716.1 | 3.82 | 0.0227 | ||
| CX604177.1 | 2.70 | 0.0015 | ||
| Heparan sulfate 3-O-sulfotransferase 3A1 | HS3ST3A1 | CX595901.1 | 2.61 | 0.0061 |
| Matrix metalloproteinase 1 (collagenase) | MMP1 | peMMP1 | 4.61 | 0.0080 |
| Nexin-1 | PN-1 | CX604123.1 | 2.27 | 0.0071 |
| Procollagen C-endopeptidase enhancer 2 | PCOLCE2 | CX597547.1 | 4.63 | 0.0041 |
| CX601347.1 | 2.08 | 0.0036 | ||
| CX604313.1 | 1.89 | 0.0013 | ||
| CX605197.1 | 4.64 | 0.0322 | ||
| CX605337.1 | 4.31 | 0.0038 | ||
| Serine proteinase inhibitor, clade A, member 5 | SERPINA5 | CX598843.1 | 3.27 | 0.0038 |
| Sulfatase 1 | SULF1 | CX596711.1 | 2.83 | 0.0043 |
| Tissue inhibitor of metallopeptidase 2 | TIMP2 | CX605012.1 | 4.48 | 0.0050 |
Gene Name & Gene Symbol: gene identity of best BLAST match homologue to cDNA or plasmid; GenBank ID: Accession number of equine cDNA spotted on the microarray (†: some IDs represent plasmid designation); Fold Change (A/N): Relative Adult/Neonate fold change; p-value: one-sample t-test p-value for probe across the four biological replicates in the total sample set.