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. 2008 Nov 6;6:34. doi: 10.1186/1741-7015-6-34

Table 1.

Distribution of valvular regurgitation at initial echocardiogram in 4825 women exposed to fenfluramine and/or dexfenfluramine

Ages
<20 (n = 25) 20–29 (n = 386) 30–39 (n = 900) 40–49 (n = 1442) 50–59 (n = 1279) 60–69 (n = 610) 70+ (n = 183) All ages (n = 4825)
Aortic regurgitation
 none (%) 96.0 85.8 75.4 65.4 59.5 59.8 53.6 66.3
 trace (%) 4.0 10.1 14.7 17.6 19.9 20.7 29.5 17.8
 mild (%) 0 3.1 7.8 11.2 13.4 12.8 11.5 10.7
 moderate (%) 0 1.0 2.0 5.1 6.6 5.7 4.9 4.7
 severe (%) 0 0 0.11 0.62 0.55 0.98 0.55 0.50
Mitral regurgitation
 none (%) 64.0 42.2 36.4 29.8 24.9 22.6 18.6 29.6
 trace (%) 32.0 50.8 50.7 54.4 54.3 54.1 48.6 53.0
 mild (%) 4.0 4.9 10.3 11.2 13.9 13.6 13.1 11.6
 moderate (%) 0 1.8 2.2 4.2 5.5 8.7 15.3 4.9
 severe (%) 0 0.26 0.33 0.49 1.5 0.98 4.4 0.91
Tricuspid regurgitation
 none (%) 56.0 22.8 24.4 22.8 21.1 18.4 15.3 22.0
 trace (%) 28.0 63.5 60.3 62.1 60.0 62.1 60.1 61.1
 mild (%) 16.0 11.9 12.6 12.1 12.9 11.5 12.6 12.3
 moderate (%) 0 1.8 2.6 2.5 5.2 6.6 10.4 4.0
 severe (%) 0 0 0.11 0.55 0.70 1.5 1.6 0.62