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Inhibition of HIV-1 mediated cell-cell fusion by gp41 MPR derived peptides
| IC50g (nM, Mean ± S.D.) |
IC50 (nM, Mean ± S.D.) |
||
| N36 | >1000 | LZ | > 1000 |
| P1 | 913 ± 13.6 | P1 + LZ | 923.4 ± 11.7 |
| T20 | 78 ± 5.6 | T20 + LZ | 579 ± 3.5 |
| P5 | 60 ± 2. | P5 + LZ | 61 ± 1.5 |
| P5L | 90 ± 1.7 | P7 | 560 ± 10.7 |
Note: Peptides P5L and P7 are recombinants the other chemically synthesized
