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Growth of heterotopic LL tumors in C57Bl/6 mouse strainsa
| Strain | % Mice with tumors (N) | Median survivalb (days) |
|---|---|---|
| WT | 100 (70) | 17 |
| SCID | 100 (23) | 15 |
| DKO (class I + II knockout) | 100 (9) | 18 |
aMice were injected subcutaneously in the flank with 5 × 105 LL tumor cells. Tumor growth was monitored daily by palpation and verified microscopically at necropsy
bMice were sacrificed when a tumor diameter reached 15 mm
