Table 3.

Mechanical testing of femur diaphysis

Genotype	n	Area moment of inertia, mm4	Maximal load, N	Elastic modulus, MPa	Maximal stress, GPa
WT	6	0.34  ± 0.01	28.4  ± 1.9	3.8  ± 0.2	132  ±  8
ERKO	9	0.24  ± 0.01**	23.2  ± 0.7*	4.4  ± 0.3	140  ±  5
BERKO	5	0.32  ± 0.03	26.5  ± 2.1	3.5  ± 0.3	122  ±  10
DERKO	5	0.26  ± 0.02**	24.3  ± 1.6	3.5  ± 0.1	140  ±  6

Values are presented as mean ± SEM. Data first were analyzed by a one-way ANOVA, followed by Student–Newman–Keuls multiple range test. *, P < 0.05; **, P < 0.01, both versus WT.