Table 1.
List of genes differentially expressed in A-FOS expressing animals 24 hours after cocaine. The table includes the Affymetrix probe set ID for each gene along with its official gene symbol and description/function taken from the NCBI Entrez gene databases (if available). The expression profile group to which a particular gene was assigned is also indicated, using the same letters as in Fig. 6. The number under Ref on the right indicates where a gene has previous been reported in microarray studies of psychostimulants (1= (Yao et al., 2004), 2= (McClung and Nestler, 2003))
| Probe Set ID | Expression Profile Groups | Gene Symbol | Gene Description | Refs |
|---|---|---|---|---|
| 1423126_at | a | Atp1b3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 1 |
| 1434026_at | a | Atp8b2 | atpase, class I, type 8B, member 2: cation transport ATPase activity | 1 |
| 1428845_at | a | Bclaf1 | BCL2-associated transcription factor 1 | |
| 1455771_at | a | Bzrap1 | benzodiazapine receptor associated protein 1 | |
| 1426124_a_at | a | Clk1 | CDC-like kinase 1:dual specificity protein kinases found in the nucleus | |
| 1417492_at | a | Ctsb | cathepsin B : lysosomal cysteine proteinase | |
| 1424288_at | a | D5Wsu46e | unknown | |
| 1426380_at | a | Eif4b | eukaryotic translation initiation factor 4B | 1 |
| 1426810_at | a | Jmjd1a | jumonji domain containing 1A: encodes a zinc finger protein | |
| 1458428_at | a | Kcnt1 | potassium channel, subfamily T, member 1: cation transport | |
| 1449172_a_at | a | Lin7b | lin 7 homolog b : Veli isoform associates with CASK and Mint1 | |
| 1418763_at | a | Nit2 | nitrilase family, member 2 | |
| 1426548_a_at | a | none | unknown | |
| 1429344_at | a | none | unknown | |
| 1435744_at | a | none | unknown | |
| 1439194_at | a | none | unknown | |
| 1443287_at | a | none | unknown | |
| 1444345_at | a | none | unknown | |
| 1422622_at | a | Nos3 | nitric oxide synthase 3, endothelial cell | |
| 1447640_s_at | a | Pbx3 | pre B-cell leukemia transcription factor 3 | |
| 1417919_at | a | Ppp1r7 | protein phosphatase 1, regulatory (inhibitor) subunit 7 | 1 |
| 1441963_at | a | Prosapip1 | unknown | |
| 1429614_at | a | Prpf18 | PRP18 pre-mRNA processing factor 18 homolog | |
| 1449957_at | a | Ptprv | protein tyrosine phosphatase, receptor type, V | 1,2 |
| 1439630_x_at | a | Sbsn | suprabasin | |
| 1455493_at | a | Syne1 | synaptic nuclear envelope 1 | |
| 1420418_at | a | Syt2 | synaptotagmin 2: membrane bound, calcium ion binding, transporter activity | 1,2 |
| 1422168_a_at | b | Bdnf | brain derived neurotrophic factor | |
| 1417606_a_at | b | Calr | calreticulin | 1,2 |
| 1450005_x_at | b | Egfl9 | EGF-like-domain, multiple 9 | |
| 1435473_at | b | Gm347 | unknown | |
| 1424367_a_at | b | Homer2 | homer homolog 2 | |
| 1454784_at | b | Hs3st2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 1 |
| 1421926_at | b | Mapk11 | mitogen-activated protein kinase 11 | 1 |
| 1417569_at | b | Ncald | neurocalcin delta : calcium ion binding | |
| 1433909_at | b | none | unknown | |
| 1439808_at | b | none | unknown | |
| 1441069_at | b | none | unknown | |
| 1456684_at | b | none | unknown | |
| 1434270_at | b | Nptxr | neuronal pentraxin receptor | |
| 1428393_at | b | Nrn1 | neuritin 1: an immediate-early gene induced by Ca(2+) influx | 1,2 |
| 1450945_at | b | Prkca | protein kinase C, alpha | 1,2 |
| 1436182_at | b | Sat61 | special AT-rich sequence binding protein 1 | |
| 1440128_s_at | b | Sez6l | seizure related 6 homolog (mouse)-like | |
| 1426367_at | c | Cab39l | calcium binding protein 39-like | |
| 1424633_at | c | Camk1g | calcium/calmodulin-dependent protein kinase I gamma | 1,2 |
| 1423286_at | c | Cbln1 | cerebellin 1 precursor protein | |
| 1436529_at | c | Gpr123 | G protein-coupled receptor 123 | |
| 1421350_a_at | c | Grip1 | glutamate receptor interacting protein 1 | |
| 1417435_at | c | Large | like-glycosyltransferase | |
| 1418104_at | c | Nrip3 | nuclear receptor interacting protein 3 | |
| 1434530_at | c | Odz4 | odd Oz/ten-m homolog 4 (Drosophila) | |
| 1425110_at | c | Sorcs3 | sortilin-related VPS10 domain containing receptor 3 | |
| 1434934_at | d | Atpaf1 | ATP synthase mitochondrial F1 complex assembly factor 1 | |
| 1419696_at | d | Cd4 | CD4 antigen | |
| 1428147_at | d | Coro7 | coronin 7: Golgi apparatus, integral to membrane of membrane fraction | |
| 1434049_at | d | Entpd3 | ectonucleoside triphosphate diphosphohydrolase 3 | |
| 1453321_at | d | Fndc1 | fibronectin type III domain containing 1 | |
| 1457189_at | d | Itpr1 | inositol 1,4,5-triphosphate receptor 1 | |
| 1435649_at | d | Nexn | nexilin : nF actin binding protein | |
| 1439724_at | d | none | Ria8: Regulates Golf G-protein signalling | |
| 1418894_s_at | d | Pbx2 | pre B-cell leukemia transcription factor 2 | |
| 1449851_at | d | Per1 | period homolog 1 | 1,2 |
| 1442068_at | d | Pinx1 | PIN2-interacting protein 1 | |
| 1433907_at | d | Pknox2 | Pbx/knotted 1 homeobox 2 | |
| 1422620_s_at | d | Ppap2a | phosphatidic acid phosphatase 2a | |
| 1454902_at | d | Prkcz | protein kinase C, zeta | |
| 1419137_at | d | Shank3 | SH3/ankyrin domain gene 3 | 1 |
| 1423258_at | d | Syt9 | synaptotagmin 9 | 1,2 |
| 1426997_at | d | Thra | thyroid hormone receptor alpha | 1 |
| 1456011_x_at | e | Acaa1 | acetyl-Coenzyme A acyltransferase 1 | |
| 1431402_at | e | Kirrel3 | kin of IRRE like 3 | |
| 1426233_at | e | Map2k4 | mitogen activated protein kinase kinase 4 | |
| 1439502_at | e | none | unknown | |
| 1441753_at | e | none | unknown | |
| 1454487_at | e | none | unknown | |
| 1457536_at | f | Gpc5 | glypican 5 | |
| 1428508_at | f | none | unknown | |
| 1432680_at | f | none | unknown | |
| 1441172_at | f | none | unknown | |
| 1447478_at | f | none | unknown | |
| 1451046_at | f | Zfpm1 | zinc finger protein, multitype 1 | |
| 1418178_at | g | Ina | internexin neuronal intermediate filament protein, alpha | 2 |
| 1427017_at | g | Satb2 | special AT-rich sequence binding protein 2 |