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. 2008 Aug 10;30(4):263–272. doi: 10.1007/s11357-008-9067-y

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© Springer 2008

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Fig. 2 a, b — Age-related decrease in input/output curve is rescued by blueberry-enriched diet. a Stimulus intensity vs fiber potential in CA1 from young (closed circles; n = 8), aged control diet (closed triangles; n = 6) and aged blueberry diet animals (open circles; n = 6). The fiber potential from a given stimulus intensity was reduced in aged animals on control or blueberry diet compared with young (the slope of the regression line was 0.134 ± 0.007, 0.073 ± 0.004, and 0.086 ± 0.004 in young, aged controls, and aged blueberry diet, respectively, p < 0.001 young vs aged control and aged blueberry). b I/O curve showing initial slope of the EPSP as a function of the fiber potential evoked in young (closed circles; n = 8), aged control diet (closed triangles; n = 6) and aged blueberry diet (open circles; n = 6). A linear regression was preformed on each group. The resulting slopes of the linear portion of the I/O curves were 2,702 ± 63, 1,223 ± 73 and 2,988 ± 156 for young, aged control and aged blueberry, respectively. The resulting I/O curve slopes from the young and aged blueberry diet animals were significantly different from the aged control diet by one-way ANOVA with Tukey’s post hoc (p < 0.001 young vs aged control and aged blueberry vs aged control)