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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2008 Aug 8;232(3):469–477. doi: 10.1016/j.taap.2008.08.001

Figure 5.

Figure 5

Competition for binding of IL-8 by other proteins. SRM2975 (25 μg/ml) was incubated with radiolabeled IL-8 at 500 pg/ml in the presence of a range of concentrations of either BSA (open squares) or cytochrome C (closed triangles). Following centrifugation, the amount of labeled IL-8 associated with the particles was determined. Curves indicate the fit to a one-site competition model, using the maximum binding as the baseline. Data shown are from one of three similar experiments. Error bars represent the SEM of duplicate measurements.