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. Author manuscript; available in PMC: 2008 Nov 21.
Published in final edited form as: Comb Chem High Throughput Screen. 2007 Dec;10(10):857–876. doi: 10.2174/138620707783220365

Table 1. Natural Product DKPs and Their Biological Activities (DKP Core Structures are Highlighted in Bold).

Natural Product Structure Isolated from Biological Activites Ref.
Bicyclomycin graphic file with name nihms78771t1.jpg Streptomyces sp. (Gram-positive bacteria) Antibiotic against Gram-negative and Gram-positive bacteria [20, 21]
Brevicompanine graphic file with name nihms78771t2.jpg Penicillium brevicompactum (fungus) Plant growth promoter [22]
Chaetocochins graphic file with name nihms78771t3.jpg Chaetomium cochliodes (fungus) Cytotoxins (target unknown) [23]
Leptosins graphic file with name nihms78771t4.jpg Leptoshaeria (marine fungus) Antitumor agents that inhibit DNA topoisomerases [24]
MPC1001 graphic file with name nihms78771t5.jpg Cladorrhinum sp. (fungus) Antitumor antibiotic [25]
Phenylahistin graphic file with name nihms78771t6.jpg Aspergillus ustus (fungus) Mammalian cell cycle inhibitor [26]
Rhodotorulic acid graphic file with name nihms78771t7.jpg Rhodotorula sp. (yeast) Siderophore in E. coli [27]
Verrucologens graphic file with name nihms78771t8.jpg Penicillium verruculosum (fungus) Neurotoxins that block Ca2+-activated K+ channels [28]