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. Author manuscript; available in PMC: 2008 Nov 21.
Published in final edited form as: Comb Chem High Throughput Screen. 2007 Dec;10(10):857–876. doi: 10.2174/138620707783220365

Table 3. Comparison of Isolated Yields Obtained Through Conventional or MW-Assisted Heating in Various Solvents [63].

DKP Yield (%) Δa Yield (%) MWb
H2O Toluene/2-BuOH Toluene t-BuOH H2O Toluene/2-BuOH Toluene t-BuOH
a 41 8 20 62 73 14 18 10
b <5 9 5 41 81 <5 10 4
c 57 6 5 10 70 6 <5 12
d 5 5 10 10 97 12 12 15
e 7 32 24 37 68 17 14 24
f <5 <5 7 10 71 21 7 6
g 7 5 <5 8 63 15 8 8
h 35 7 22 41 84 12 <5 6
i 33 51 29 88 70 10 14 10
j 28 23 12 37 83 5 12 <5
k 89 88 83 93 93 73 70 76
a

Reactions were heated to reflux for 12 h.

b

Reactions were heated to 40°C above solvent boiling point for 10 min.