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. 2008 Nov 24;205(12):2915–2927. doi: 10.1084/jem.20080174

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© 2008 Ishimaru et al.

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Figure 2. — Immune responses in RbAp48-Tg mice. (A and B) Activation markers and cytokine production of CD4⁺ T cells of cLNs from WT and RbAp48-Tg mice at 32 wk of age. (C) Autoantibodies of sera from RbAp48-Tg mice at 28–32 wk of age. (D) CD5⁺B220⁺ population of spleen from RbAp48-Tg and WT mice at 20 and 40 wk of age was analyzed by flow cytometry. Results are representative of means ± SE of five to seven mice in three independent experiments. *, P < 0.05; **, P < 0.005; WT versus RbAp48-Tg mice.