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. Author manuscript; available in PMC: 2009 Oct 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2008 Jul 15;232(2):337–350. doi: 10.1016/j.taap.2008.07.004

Figure 6.

Figure 6

CV-1 cells were cotransfected with Gal-L-PXR (A) or Gal-L-SXR (B) together with MH100-tk-luc, CMX-β-gal. In panels (C) and (D), cells were transfected with full length PXR or SXR, together with hRXRalpha, (DR3)3-tk-luc and CMX-β-gal. Transfected cells were incubated with media containing indicated amount of ligand or solvent control for 18–24 h before subjected to luciferase and β-gal assay. Transcriptional activation was assessed by the relative luciferase activity normalized by β-gal activity. Figures represent means ± SD.