The ratio of bioluminescence of 10% (w/v) BC suspension femora, LPS, and PBS injected femora versus bioluminescence of the corresponding non-operated contralateral femur from day 0 to 14 post-injection of macrophages. The Y-axis is a normalized ratio of bioluminescence (unit: p/s/cm2/sr) from the operated femur versus non-operated femur in each animal. The values are mean ± SE. Number of animals in BC and saline injected groups are 11 and 8, respectively. # and *: indicates BC treatment group compared with PBS injected group at the same time point is statistically significant, p < 0.1 and p < 0.05, respectively;