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Stoichiometry of inhibition. Matriptase (19.2 μM) was pre-incubated with various concentrations of AAT (from 1:0.25 to 1:10, [Matriptase]:[AAT] molar ratio) for 18 hours before assay of matriptase inhibition. Data were fitted with linear regression (r2 = 0.882; P < 0.01; X intercept = 1). Figure is characteristic of two experiments with similar results.
