Figure 2.

Demonstration of lytic infection of primary human pulmonary microvascular endothelial cells (HMVEC-L) infected with HHV-8. Green staining indicates LANA-1, red staining indicates K8.1 (a marker of lytic replication), and blue is a Hoechst nuclear stain. (a) BCBl-1 cells (reservoir cells for HHV-8) induced to enter lytic infection. These cells serve as a positive control. (b) HMVEC-L 72 hours after exposure to HHV-8. (c) Mock-infected HMVEC-L (negative control) treated in identical fashion as in b, though without exposure to HHV-8.