TABLE 2.
GENES ALTERED IN THEIR EXPRESSION BY HHV-8 INFECTION RELATED TO CELLULAR APOPTOSIS
| Gene | Gene Symbol | Fold Change in HHV-8 Infection |
|---|---|---|
| BCL2-like 11 (apoptosis facilitator) | BCL2L11 | 0.5 |
| Angiopoietin 2 | ANGPT2 | 5.0 |
| Vascular endothelial growth factor receptor | FLT1 | 6.0 |
| Serine/threonine kinase 17b (apoptosis-inducing) | STK17b | 0.5 |
| Transforming growth factor β1 | TGF-β1 | 0.7 |
| Transforming growth factor β2 | TGF-β2 | 0.29 |
| Bone morphogenic protein receptor 1a | BMPR1a | 0.5 |
| Caspase 1 | CASP1 | 2.0 |
| Caspase 4 | CASP4 | 1.9 |
| TNF receptor superfamily 6 | TNFRSF6 | 2.0 |
Definition of abbreviation: HHV-8, human herpesvirus-8.
Relative fold change of gene expression of HHV-8 infected cells as compared to mock infected cells is listed.