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. Author manuscript; available in PMC: 2009 Nov 1.

Published in final edited form as: Peptides. 2008 Jul 17;29(11):2061–2065. doi: 10.1016/j.peptides.2008.07.001

Upper panel compares Ki as assessed by brain perfusion in fed 8 week ( n = 15), fed retired breeder (n = 15), fasted 8 week (n = 11) and fasted retired breeder (n = 6) mice. Fasting significantly increased transport of ghrelin in 8 week old mice. Lower panel shows that intravenous injection of ghrelin with the triglyceride triolein increased ghrelin transport across the BBB (n = 11/group).

Upper panel compares Ki as assessed by brain perfusion in fed 8 week ( n = 15), fed retired breeder (n = 15), fasted 8 week (n = 11) and fasted retired breeder (n = 6) mice. Fasting significantly increased transport of ghrelin in 8 week old mice. Lower panel shows that intravenous injection of ghrelin with the triglyceride triolein increased ghrelin transport across the BBB (n = 11/group).