Table 2.

Nonparametric LOD scores for overall and maternal-only analyses of individual sites and combined data sets.

		JHU		UAB		JHU + UAB
		ALL	MAT	ALL	MAT	ALL	MAT
Marker	cM	N=147	N=48	N=140	N=20	N=287	N=68
D10S1228	57.4	0.50	0.44	0.00	0.00	0.11	0.23
D10S1426	59	1.02	1.11	0.00	0.00	0.18	0.52
D10S507	59.8	1.02	1.62	0.00	0.00	0.18	0.91
D10S1169	60.6	1.06	1.97	0.00	0.00	0.19	1.23
D10S1208	63.3	2.02	2.91	0.00	0.00	0.47	2.16
D10S1247	63.3	2.07	2.99*	0.00	0.00	0.51	2.24
D10S1217	63.83	1.91	2.71	0.00	0.01	0.48	2.12
D10S1233	66.5	1.42	2.73	0.00	0.22	0.52	2.81
D10S1413	67.39	1.29	2.69	0.00	0.32	0.54	2.92
D10S1724	70.23	1.34	2.38	0.04	0.81	0.98	3.20
D10S1220	70.2	1.26	2.45	0.04	0.83	0.94	3.28
D10S1784	72.9	1.08	2.56	0.11	0.90**	0.98	3.46
D10S539	72.9	1.10	2.59	0.07	0.60	0.89	3.16
D10S1642	74.5	1.04	2.89	0.08	0.66	0.94	3.51
D10S1221	75.6	1.11	2.90	0.17	0.85	1.11	3.73***
D10S464	79	0.85	1.75	0.33	0.92	0.12	2.66
D10S1225	80.8	0.53	0.85	0.29	0.86	0.81	1.63

Shading corresponds to the original 1LOD interval defined by the JHU maternal families.(Bassett, Avramopoulos, and Fallin 2002)

^*Empirical sig of change in score, JHU ALL to JHU MAT; p=0.021

^**Empirical sig of change in score, UAB ALL to UAB MAT, within the 1-LOD interval; p=0.054.

^***Empirical sig of change in score, JHU+UAB ALL to JHU+UAB MAT; p=0.002; Empirical significance of observed linkage; p=0.005.