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Time course of bovine organotypic raft development. Organotypic rafts were cultured by using mouse 3T3 fibroblasts and bovine keratinocytes. Samples were taken at the times shown after lifting the raft to the air–liquid interface. Sections of the rafts were stained with H&E. The stratum corneum (sc), stratum granulosum (sg), stratum spinosum (ss), and stratum basale (sb) are indicated by arrows.
