Table 1.
Ability of xenografts to produce infectious BPV-1
| Group* | Fibroblasts | “Take-rate”† | Fibroma‡ | Virus production§ |
|---|---|---|---|---|
| None | BALB | 1 /3 | 0 /1 | 0/1 |
| BALB/BPV | 7 /14 | 4 /7 | 0/5 | |
| Total | 8 /17 | Total: 0/6 | ||
| DNA | BALB | 3 /5 | 0 /3 | 2/2 |
| BALB/BPV | 12 /13 | 11 /12 | 6/10 | |
| Total | 15 /18 | Total: 8/12 | ||
| Virus | BALB | 4 /4 | 1¶ /4 | 3/4 |
| BALB/BPV | 11 /14 | 10 /11 | 3/7 | |
| Total | 15 /18 | Total: 6/11 |
*Input BPV-1.
†Grafts per no. mice.
‡Fibromas per no. grafts.
§Grafts producing virus per no. grafts tested.
¶A small fibroma arose from infection of fibroblasts in the collagen.