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. Author manuscript; available in PMC: 2008 Nov 24.
Published in final edited form as: Nature. 2005 Jan 13;433(7022):171–176. doi: 10.1038/nature03240

Figure 2.

Figure 2

Cdc14 phosphatase regulates microtubule dynamics in mitosis. Anaphase spindles in the absence of Cdc14 activity in strain Y1594 (MATa cdc14-1 TyEGFP-TUB1) maintain high microtubule turnover, and Cdc14 expression in metaphase arrested strain Y1533 (MATα MET-CDC20 GAL-CDC14-Pk yEGFP-TUB1) is sufficient to silence microtubule dynamics. Cdc14 expression together with TEV protease in strain Y1539 (as Y1533, but GAL-TEV SCC1TEV) generates a stable anaphase spindle. See Fig. 1 for key to symbols.