Table 1.
Time (h) | Ghrelin | NaCl | Desacyl ghrelin | Ghrelin plus desacyl ghrelin | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
13 μg/kg | 0.15 M | 64 μg/kg | 127 μg/kg | 13 μg/kg + 64 μg/kg | 13 μg/kg + 127 μg/kg | ||||||
FI (g/kg) | FI (g/kg) | FI-reduction to ghrelin (%) | FI (g/kg) | FI-reduction to ghrelin (%) | FI (g/kg) | FI-reduction to ghrelin (%) | FI (g/kg) | FI-reduction to ghrelin (%) | FI (g/kg) | FI-reduction to ghrelin (%) | |
FI = Food intake, values are mean ± SEM of n=10-13 rats/group; p*=<0.05. | |||||||||||
0.5 | 6.20±0.56 | 1.49±0.72* | −75.93 | 0.61±0.32 | −90.22* | 1.53±0.92 | −75.37* | 2.44±0.77 | −60.68* | 2.50±0.86 | −59.67* |
1 | 7.28±1.00 | 1.49±0.72* | −79.51 | 2.05±0.99 | −71.82* | 2.34±1.00 | −67.77* | 2.44±0.77 | −66.41* | 3.02±1.10 | −58.51* |
2 | 7.73±1.06 | 2.65±0.93* | −65.68 | 2.85±1.45 | −63.11* | 3.38±1.77 | −56.27* | 2.44±0.77 | −68.39* | 3.02±1.10 | −60.95* |
3 | 7.77±1.06 | 2.66±0.92 | −65.75 | 2.85±1.45 | −63.32* | 4.43±2.18 | −43.06 | 3.21±1.09 | −58.71 | 3.02±1.10 | −61.17* |
4 | 7.77±1.06 | 2.66±0.92* | −65.75 | 3.44±1.80 | −55.70* | 4.43±2.18 | −43.06* | 3.26±1.08 | −58.06 | 3.04±1.10 | −60.94* |
5 | 7.79±1.05 | 2.68±0.92* | −65.75 | 3.44±1.80 | −55.76* | 4.43±2.18 | −43.14* | 3.65±1.18 | −53.12 | 3.05±1.10 | −65.62* |