Table 3.
Temporal | Cingulate | ||||||
---|---|---|---|---|---|---|---|
Aβ40 | Aβ42 | Aβ42 | |||||
r | p | r | P | r | p | ||
Blessed DRS prior to death | Tris | −0.040 | 0.854 | 0.252 | 0 234 | 0.042 | 0.845 |
Triton | 0.485 | 0.016 | −0.185 | 0.388 | |||
SDS | 0.439 | 0.032 | 0.168 | 0.432 | |||
FA | −0.075 | .728 | −0.065 | 0.763 | −0.189 | 0.376 | |
Illness Duration | Tris | 0.567 | 0.002 | 0.130 | 0.518 | 0.117 | 0.568 |
Triton | 0.286 | 0.149 | −0.039 | 0.848 | |||
SDS | −0.087 | 0.667 | 0.199 | 0.330 | |||
FA | 0.510 | 0.007 | −0.097 | 0.629 | 0.004 | 0.986 | |
F | p | F | P | F | p | ||
ApoE | Tris | 5.154 | 0.014 | 0.226 | 0.799 | 0.508 | 0.608 |
Triton | 0.874 | 0.430 | 0.603 | 0.556 | |||
SDS | 1.272 | 0.299 | 0.087 | 0.917 | |||
FA | 9.343 | 0.001 | 1.695 | 0.205 | 0.278 | 0.760 | |
β | p | β | P | β | p | ||
Rate of cognitive decline | Tris | −1.237 | 0.268 | 0.005 | 0.997 | 2.070 | 0.145 |
Triton | 1.750 | 0.200 | −0.112 | 0.940 | |||
SDS | 3.506 | <0.001 | −2.747 | 0.011 | |||
FA | −2.106 | 0.070 | 1.019 | 0.375 | −2.477 | 0.020 |
All analyses reflect unadjusted models using raw data, except Blessed correlations which include time from last evaluation until death as a covariate. The reported β in the GEE analysis is that of the time × Aβ interaction term; positive values indicate a more rapid cognitive decline for subjects with measured Aβ in the upper median.