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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: J Mol Cell Cardiol. 2008 Aug 27;45(6):832–838. doi: 10.1016/j.yjmcc.2008.08.004

Fig. 1.

Fig. 1

Identification of the angiotensin II-responsive ARE. (A) Luciferase reporter constructs containing various lengths of Kv4.3 3′UTR. These constructs were based on the PGL3 plasmid. Blue represents the plasmid backbone of PGL3, yellow represents the coding sequence of luciferase, orange represents Kv4.3 3′UTR sequence, and green represents the SV40 polyadenylation signal sequence. Note that different regions of the Kv4.3 3′UTR were deleted. Numbers in the name of the deletion constructs refer either to the number of kb remaining from the 3′UTR starting at its 5′ end (e.g. PG0.4B) or the number of kb deleted from the 3′UTR starting at its 5′ end (e.g. PGΔ1.8). (B) The Ang II effect on each Kv4.3 3′UTR reporter construct. Cardiac myocytes were treated with either vehicle or 100 nmol/L Ang II for 7 h. Data are from 3 to 9 independent experiments. **p<0.05.