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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: J Mol Cell Cardiol. 2008 Aug 27;45(6):832–838. doi: 10.1016/j.yjmcc.2008.08.004

Fig. 2.

Fig. 2

Identification of the Ang II-sensitive ARE. (A) AREs in the mouse Kv4.3 3′ untranslated region (3′UTR). Sequences conserved in human Kv4.3 are indicated with an asterisk (*). Numbers indicate number of nucleotides downstream of the stop codon (i.e., from the start of the 3′UTR). (B) The PG1.4-m2 mutant, which alters ARE #2, blocks the Ang II effect. In contrast, disrupting ARE #1 does not alter Ang II-induced destabilization. n=4. **p<0.01.