Figure 7.

Alignment of the human ∼300-bp WNT5A-responsive element with its counterpart in mouse 73% sequence identity. Human genomic upstream region of WNT5A was compared to the mouse counterpart and a percent identity plot (PIP) was generated. There are several regions of homologous sequence in the 100-kb 5′-upstream region. None of these homologous regions match known genes or expressed sequence tags and are therefore assumed to be noncoding regulatory sequences. The NACE-enriched ∼300-bp fragment (bar) overlaps one of these homologous regions that share more than 70% identity with the mouse.