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. Author manuscript; available in PMC: 2009 Nov 12.
Published in final edited form as: Eur J Pharmacol. 2008 Aug 30;597(1-3):39–45. doi: 10.1016/j.ejphar.2008.08.025

Fig. 3.

Fig. 3

The effect of clocinnamox (CCAM) treatment on the analgesic potency of hydromorphone. Mice (N=6–10/treatment) were injected i.p. with CCAM or saline (control) and 24h later hydromorphone cumulative dose response studies (tail flick) were conducted. The data for control represent the mean of three experiments, while the CCAM treatment results are from one experiment for each dose. The data plotted are the mean tail flick latency as a function of cumulative dose. EC50 estimates were calculated for each treatment (see Table 1).