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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Xenotransplantation. 2008 Jul-Aug;15(4):268–276. doi: 10.1111/j.1399-3089.2008.00480.x

Table 1.

Prospective non-Gal anti-EC targets
Protein Name MW (kDa) Function
P07589 Fibronectin a 249 Extracellular matrix
Q92896 MG-160 a 180 Membrane protein
Q9Y4L1 ORP150 a 111 Stress response
P34932 HSP70RY a,b 94 Stress response
P14625 HSP90B1 a,b 92 Stress response
P38646 GRP75 a 74 Stress response
P11021 GRP78 a 72 Stress response
P11142 HSC70 a,b 70 Stress response
P79134 Annexin A6 a 69 Inflammation
P10809 HSP-60 a,b 61 Stress response
P40227 TCP1a,b,c 58 Stress response
P08670 Vimentin a,b 53 Cytoskeleton
P19619 Annexin A1 a 38 Inflammation
P07355 Annexin A2 b 38 Inflammation
Additional non-Gal anti-EC targets
Protein Name MW (kDa) Function
Q14764 Major vault protein a 99 Signaling
P55072 Transitional ER ATPaseb 89 Biosynthesis
P16276 Aconitate hydratasea 85 Metabolism
P27594 Mx1a,b 75 Unknown
Q13409 Dynein intermediate chain a 71 Cytoskeletal
P13796 Plastin-2 b 70 Cytoskeletal
P37879 Lysyl-tRNA synthetase a 68 Biosynthesis
P26038 Moesin a 68 Cytoskeletal
Q32LP2 Radixin b 68 Cytoskeletal
P14866 hnRNP-La 60 Biosynthesis
Q5R8T5 Tyrosyl-tRNA synthase a,b 59 Biosynthesis
P14618 Pyruvate kinasea 58 Metabolism
P38657 Protein disulfide isomerasea 57 Biosynthesis
P20000 aldehyde dehydrogenase b 56 Metabolism
P00829 ATP synthase b-chaina,b 56 Metabolism
Q2TBU9 RuvB-like 2 b 51 Biosynthesis
P81948 Tubulin b 50 Cytoskeletal
P49410 Elongation factor Tua 49 Biosynthesis
P17980 26S protease regulatory subunit b 49 Catabolism
P06733 Alpha-enolasea,b 47 Metabolism
P61158 actin like protein 3b 47 Cytoskeletal
P63261 actina,b 42 Cytoskeletal
P00346 Malate dehydrogenase a 35 Metabolism
P15924 desmoplakin b 33 Cytoskeletal
a

Identified with antibody from sensitized baboon serum.

b

Identified with antibody recovered from GT-KO heart transplants.

c

Antibody responses to TCP-1 beta, theta and zeta subunits detected. Molecular weights are based on the values listed in the UniProtKB/Swiss-Prot database.