. Author manuscript; available in PMC: 2008 Nov 25.

Published in final edited form as: J Nutr. 2008 Sep;138(9):1677–1683. doi: 10.1093/jn/138.9.1677

TABLE 2.

Effect of long-term EGCG treatment on plasma biomarkers and liver pathology in C57BL/6J mice fed a high-fat diet for 16 wk (Expt. 2)¹

	LF	HF	HFE
n	11	21	21
Plasma biomarkers²
Insulin, pmol/L	74.13 ± 5.17^a	867.24 ± 100^b	353.44 ± 86.21^a
HOMA-IR	3.12 ± 0.37^a	74.47 ± 6.47^b	17.41 ± 12.48^a
Cholesterol, mmol/L	2.63 ± 0.15^a	5.57 ± 0.13^b	4.21 ± 0.16^c
Plasma MCP-1, pmol/L	0.86 ± 0.15^a	6.70 ± 0.99^b	2.04 ± 0.33^a
Liver pathology
Liver wt/BW, g/g	0.036 ± 0.0006^a	0.045 ± 0.002^b	0.035 ± 0.001^a
Fatty liver incidence	0/12^a	21/22^b	4/22^a
Liver triglycerides, μmol/g tissue	49.69 ± 7.17^a	200.76 ± 15.24^b	61.37 ± 21.34^a
Plasma ALT, U/L	13.23 ± 1.50^a	105.21 ± 15.58^b	35.25 ± 5.47^a

Data are presented as means ± SEM. Means in a row with superscripts without a common letter differ, P < 0.05.

Blood samples were taken in food-deprived mice.