Table 3.
Reactivity of T cells from Hu-positive patients and healthy donors
| Hu-D peptides | Hu+ patients | Hu− donors |
|---|---|---|
| 58–66 | 1/3 | 0/4 |
| 64–72 | 0/6 | 0/4 |
| 86–95 | 1/6 | 0/4 |
| 88–95 | 2/5 | 0/3 |
| 111–119 | 1/6 | 0/4 |
| 134–143 | 2/5 | 0/3 |
| 147–155 | 2/3 | 1/4 |
| 151–158 | 2/5 | 0/3 |
| 154–163 | 4/5 | 0/3 |
| 163–171 | 1/6 | 0/4 |
| 176–184 | 4/5 | 0/3 |
| 245–254 | 2/6 | 2/6 |
| 248–256 | 2/6 | 0/4 |
| 272–281 | 0/2 | 0/4 |
| 305–313 | 0/2 | 0/4 |
| 315–323 | 2/6 | 0/4 |
| 341–348 | 3/5 | 0/3 |
| 347–355 | 0/4 | 1/4 |
| 362–370 | 2/6 | 0/4 |
Results are expressed as numbers of donors having T cells secreting IFN-γ in the presence of one Hu-D peptide in the ELISPOT assay. Results presented in bold characters correspond to peptides recognized by T cells of Hu-positive patients only.