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. Author manuscript; available in PMC: 2008 Nov 25.
Published in final edited form as: Lancet Neurol. 2008 Jul;7(7):615–625. doi: 10.1016/S1474-4422(08)70137-6

Figure 2. Gain or loss in brain volume, as determined from serial MRI scans.

Figure 2

Using registration-based software, brain volume gain (red) or loss (blue) can be determined with sub-voxel accuracy from serial MRI scans. Currently, it is difficult to predict why some patients (left) have little atrophy (0·29% brain volume loss per year), whereas others (right) have a high atrophy rate (2·2% brain volume loss per year).