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. Author manuscript; available in PMC: 2008 Nov 25.
Published in final edited form as: Anticancer Res. 2008;28(3A):1441–1447.

Figure 1.

Figure 1

Purα suppresses Rad51 expression. A. The expression of Rad51 and Purα in the brain was measured during mouse development. Whole tissue protein extracts from mouse brains were prepared at postnatal days 5, 10 & 15 and were immunoblotted with antibodies against Purα, anti-PCNA, anti-Rad51 and PCNA. Grb-2 protein was used as a loading control. B. Expression of Rad51 was measured in MEFs isolated from PURA+/+ (wild-type), PUR+/- and PUR-/- mice. The lane labeled +Purα represents PUR-/- MEFs where Purα was ectopically expressed as described in Materials and Methods.