Figure 4.

Electrophysiological deficits. A, Representative traces from Wt and Kal7^KO CA1 pyramidal neurons of membrane responses to positive and negative 200 pA somatic current injections. B, Composite spontaneous EPSC frequency (N = 24 Wt, 18 KO neurons; p = 0.023; left) and LTP (N = 7 Wt, 13 KO neurons; p = 0.0079; right) data. Error bars indicate SEM. C, Averaged traces of EPSCs recorded from single CA1 pyramidal neurons from Wt and Kal7^KO mice before and within 15 min after theta burst pairing.