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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Eur J Neurosci. 2008 Apr;27(7):1771–1779. doi: 10.1111/j.1460-9568.2008.06144.x

Fig. 5.

Fig. 5

Ifenprodil inhibits the magnitude of NMDA-evoked currents in SCN neurons. Whole-cell patch clamp recording methods were used to measure NMDA currents in ventral SCN during the night in a zero Mg2+ solution. A) The current-voltage relationship of SCN neuron under baseline, NMDA (25μM), and NMDA plus ifenprodil (3μM). In this example, the drugs were applied in the bath and the neuron moved to a series of voltage steps. B) The inhibitory effects of ifenprodil (3μM) on the inward current generated in response to the focal application of NMDA (100μM). The neuron was held at -70mV during this recording.