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Disruption of MK2 expression reduces actin stress fibers. Wild-type and MK2−/− fibroblasts were grown on glass coverslips and then stained with rhodamine–phalloidin. MK2−/− MEF contained less filamentous actin than wild-type MEF in which actin was more organized into parallel stress fibers. Figure shows a representative area of several coverslips from several experiments.
