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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: J Infect Dis. 2008 Sep 1;198(5):715–722. doi: 10.1086/590504

Figure 2. Osteopontin is expressed in both brains of monkeys with SIV encephalitis and humans with HIV encephalitis.

Figure 2

(A,B) Immunohistochemical analysis revealed the presence of osteopontin (*) in the brains of monkeys with SIV encephalitis (A) and the brains of human with encephalitis (B). CD163+ perivascular cells express osteopontin in the brains of monkeys with SIV encephalitis. (C-E) Immunofluorescence was performed on brain of monkeys with SIV encephalitis. (C) Osteopontin is shown in green and DAPI in blue. (D) CD163 is shown in red with DAPI in blue. (E) Merged image, the arrows point to co-expression of CD163 and osteopontin (yellow). All images were taken through a 63× magnification lens.