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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Mol Cancer Res. 2008 Jul;6(7):1225–1231. doi: 10.1158/1541-7786.MCR-08-0078

Figure 5.

Figure 5

Suppression of Ras-induced foci formation by WT1 is mediated by MKP3. (A) NIH3T3 cells were transfected with AU5-Ras in the presence or absence of WT1 or Flag-tagged MKP3 and allowed to grow for 10 days. Foci were counted and plotted as mean number of foci/10cm plate. The relative expression of each protein, as determined by Western blot, is shown. (B) Knock down of endogenous MKP3 expression by shRNA partially blocked the WT1-mediated suppression of foci formation. Experiments were carried out independently three times in triplicate.