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. Author manuscript; available in PMC: 2008 Nov 25.
Published in final edited form as: J Neurosci Res. 2008 Jan;86(1):118–124. doi: 10.1002/jnr.21458

Fig. 4.

Fig. 4

Fast migration is unaffected by PMA-elicited cAMP elevations. A: Accumulated cAMP was measured in whole cells in the presence of IBMX (500 μM) and PMA (200 nM) in the presence or absence of 2′–5′-ddAdo (50 μM), KH7 (50 μM), 2′–5′-ddAdo (1 μM) + KH7 (50 μM), Ro 31-8220 (4 μM), or calphostin C (1 μM). Bars represent the average values for at least two independent experiments, each performed in triplicate. *P < 0.05; ns, indicates not statistically significant (P > 0.2). B: Cells, plated on laminin, were treated with NGF (200 ng/ml) + PMA (200 nM) in the presence or absence of 2′–5′-ddAdo (50 μM), Ro 31-8220 (4 μM), or calphostin C (1 μM). Bars represent the percentage of migrating cells scored 1.5 hr after treatment. Values are based on a minimum of 1,000 cells per condition with SEM indicated.