Skip to main content
. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Trends Cardiovasc Med. 2008 May;18(4):141–149. doi: 10.1016/j.tcm.2008.04.001

Figure 2.

Figure 2

Analysis of mutations located in the motor domain. Black columns correspond to the total number of observed mutations (similar plus dissimilar), dotted and striped columns correspond to the number of similar and dissimilar observed mutations, respectively. White columns correspond to the theoretical number of expected mutations. (A) Distribution of mutations in the motor domain sub-domains. For this analysis, the 50/20 loop was included in the actin-myosin interface sub-domain. (B) Comparison between mutations present in the motor domains functional sub-domains (F) and the outer structural region (S). * indicates that the observed number of mutations is significantly different than expected (p < 0.01). (C) Motor domain distribution of mutations causing dilated cardiomyopathy. Motor domain minus A-M/C corresponds to the motor domain minus the actin-myosin interface and converter regions. * indicates that the observed number of mutations is significantly different than expected (p < 0.01).