Table 1.

Classification of index biopsies: community WHO vs. EIN and panel WHO

	EIN Classification
	Cases					Controls
	Inadequate	Benign	EIN	Cancer	Total	Inadequate	Benign	EIN	Cancer	Total
EH
Classification
Community WHO
DPEM	1 (4%)	16 (64%)	4 (16%)	3 (12%)	25	-	-	-	-	-
SH	5 (10%)	26 (50%)	16 (31%)	5 (10%)	52	3 (5%)	52 (85%)	5 (8%)	1 2%)	61
CH	2 (5%)	22 (50%)	16 (36%)	2 (5%)	44	1 (1%)	63 (63%)	29 (29%)	5 (5%)	100
AH	1 (6%)	7 (41%)	6 (35%)	3 (18%)	17	0 (0%)	44 (55%)	31 (39%)	4 5%)	80
Total	9 (7%)	71 (51%)	42 (30%)	13 (9%)	138	4 (2%)	159 (66%)	65 (27%)	10 (4%)	241
	Cases					Controls
	Inadequate	Benign	EIN	Cancer	Total	Inadequate	Benign	EIN	Cancer	Total
Panel WHO
DPEM	3 (9%)	29 (88%)	1 (3%)	0 (0%)	33	4 (4%)	84 (87%)	6 (6%)	1 (1%)	95
SH	2 (5%)	32 (78%)	5 (12%)	2 (5%)	41	0 (0%)	60 (90%)	7 (10%)	0 (0%)	67
CH	2 (10%)	1 (5%)	15 (71%)	2 (10%)	20	0 (0%)	12 (28%)	23 (53%)	7 (16%)	42
AH	2 (5%)	9 (21%)	21 (49%)	9 (21%)	41	0 (0%)	3 (9%)	29 (85%)	2 (6%)	34
Total	9 (7%)	71 (51%)	42 (30%)	13 (9%)	135	4 (2%)	159 (66%)	65 (27%)	10 (4%)	238

DPEM, disordered proliferative endometrium. SH, simple hyperplasia. CH, complex hyperplasia. AH, atypical hyperplasia. EIN, endometrial intraepithelial neoplasia.

Community WHO refers to the original EH diagnoses at KPNW (1970–2003). EIN and Panel WHO were independently assigned by separate panels of gynecologic pathologists.

Cases with community WHO diagnoses of DPEM were eligible for inclusion, but all controls had a community WHO diagnosis of SH, CH, or AH.

Slides from 3 cases and 3 controls were not available for review.

Row percentages might not sum to 100 because of rounding.