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. Author manuscript; available in PMC: 2009 Aug 8.
Published in final edited form as: Biochem Biophys Res Commun. 2008 Jun 2;372(4):697–702. doi: 10.1016/j.bbrc.2008.05.132

Fig. 3. Transgenic worms expressing PrP mutants.

Fig. 3

A.) Q167R expression did not result in dumpy-like phenotypes. B.) Colocalization of MoPrP(23-231)-CFP and PrP(23-231)(Q167R)-YFP in a young adult animal co-expressing these two fusion proteins. C.) Thrashing assay. Each point represents the mean value of thrashing scores of 5 individual animals. CFP: control worm; wt: MoPrP(23-231)-CFP expressor; Q167R: MoPrP(23-231)(Q167R)-CFP expressor; wt/Q167R: co-expressors of MoPrP(23-231)-CFP and MoPrP(Q167R)(23-231)-YFP; P101L: MoPrP(23-231)(P101L)-CFP expressor. Note, only non-dumpy worms were used in this experiment.