Retinyl ester concentrations in testes, ovaries, and perigonadal fat pads for wild type, heterozygous and homozygous BCMO1-deficient mice. The bar graphs provide the mean ± SD from 4 animals/group. Baseline (0 weeks on diet) values are from 6 week-old mice. β-carotene diet (100 μg β-carotene/g diet) was provided for 4 or 7 weeks starting at 6 weeks-of-age. One-way ANOVA followed by post-hoc analysis (Bonferoni) was performed to determine whether β-carotene diet changes significantly retinoid levels in different tissues for each genotype. **, P<0.01; ***, P<0.001. Black bar, wild type mice WT; gray bar, heterozygous mice; white bar, BCMO1-deficient mice (KO).